Liposome loading method using a boronic acid compound

Details Liposome loading method using a boronic acid compound Liposome loading method using a boronic acid compound

1998-11-19

2000-04-18

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 264 43, A61K 9127

Patent

active

060512512

ABSTRACT:
A method for loading a therapeutic compound having a cis diol moiety into pre-formed liposomes is described. The method includes adding to a suspension of liposomes (i) the compound to be loaded into the liposomes and (ii) a boronic acid compound, thereby achieving accumulation of the compound within the liposomes.

REFERENCES:
patent: 5688928 (1997-11-01), Stolowitz
patent: 5831045 (1998-11-01), Stolowitz
patent: 5852178 (1998-12-01), Stolowitz

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