Liposome extrusion method

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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424 11, 264 43, A61K 3722

Patent

active

049276379

ABSTRACT:
A suspension of heterogeneous size liposomes is passed through a polymer filter having a web-like construction providing a network of interconnected, tortuous-path capillary pores, and a membrane thickness of at least about 100 microns. The processed liposomes have a selected average size less than about 0.4 microns, and a narrow size distribution.

REFERENCES:
patent: 4376059 (1983-05-01), Davis et al.
patent: 4515736 (1985-05-01), Deamer
patent: 4743375 (1988-05-01), Seita et al.
patent: 4752425 (1988-06-01), Martin et al.
patent: 4781871 (1988-11-01), West, III et al.

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