Liposome extrusion method

Details Liposome extrusion method Liposome extrusion method

1986-02-13

1988-04-12

Lovering, Richard D.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

21050023, 21050026, 424420, 424450, 4284022, 436829, 514 34, A61K 952, B01J 1302

Patent

active

047373237

ABSTRACT:
A suspension of liposomes whose sizes are predominantly greater than about 1 micron is passed through an asymmetric ceramic filter whose inner-surface pore size is about 1 micron. The processed liposomes have a selected average size of about 0.4 microns or less, depending on the number of filter cycles, and a narrow distribution.

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patent: 4394372 (1983-07-01), Taylor
patent: 4429008 (1984-01-01), Martin et al.
patent: 4460577 (1984-07-01), Moro et al.
patent: 4508703 (1985-04-01), Redziniak et al.
patent: 4529561 (1985-07-01), Hunt et al.
Norton Publication, for Ceraflo.TM. Asymmetric Ceramic Microfilters, "A New Breakthrough in Separation Technology", Norton Company, 1984, High Performance Ceramics, 1 New Bond Str., Worcester, MA 01606, Printed in U.S.A., (total 6 pp.), Membrane Filtration Publication, for Uni-Pore Membrane Filters, (total 1 p.), p. 80, Feb. 1980.
Chemistry and Physics of Lipids 12, (1973), 75-95 pp., North-Holland Publ. Co., "Studies on Phosphatidylcholine Model Membranes I., Size-Heterogeneity Effect on Permeability Mesurement, by S. E. Schullery & J. P. Garzaniti, Chem. Dept. Eastern Mich. U., U.S.A.

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