Liposome-encapsulated 5-fluoropyrimidines and methods for their

Details Liposome-encapsulated 5-fluoropyrimidines and methods for their Liposome-encapsulated 5-fluoropyrimidines and methods for their

1986-05-30

1988-07-05

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424498, 264 4, 514269, 514274, A61K 942

Patent

active

047553880

ABSTRACT:
Drugs encapsulated in liposomes are provided, where the drugs are low molecular weight, negatively charged polar drugs and the liposomes are comprised of high transition temperature phospholipids and cholesterol. Relatively large liposomes are employed to enhance drug effectiveness with viable cells.

REFERENCES:
patent: 4515736 (1985-05-01), Deamer
patent: 4564599 (1986-01-01), Janoff et al.
Heath et al., FEBS Letters, 187(1): 73-75, Jul. 1985.

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