Liposome containing immunotherapy agents for treating IgE mediat

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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A61K 3722

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active

050493906

ABSTRACT:
An immunotherapy agent for the treatment of allergy composed of an allergen encapsulated in or covalently bound to a liposome is disclosed. Use of the agent in immunotherapy results in enhanced IgG production and reduced IgE production.

REFERENCES:
patent: 4235871 (1980-11-01), Papahadjopoulous et al.
patent: 4241046 (1980-12-01), Papahadjopoulous et al.
patent: 4663167 (1987-05-01), Lopez-Berestein et al.
Chemical Abstracts 94:154477p; 95:4950.mu..
Connor, et al., "Monoclonal Antibody and Liposomes", Pharmac. Ther., vol. 22, pp. 341-365 (1985).
Chemical Abstracts 105(4): 30052X; 104(6): 39758.mu., 101(16): 137035p; 93(11): 109745t; 99(24): 200444d; 89(17): 142264a.
Ostro, M., "Liposomes", Scientific American, Jan. 1987, pp. 103-111.

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