Liposome containing hydrophobic iodine compound and X-ray...

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – X-ray contrast imaging agent

Reexamination Certificate

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C424S450000

Reexamination Certificate

active

07008614

ABSTRACT:
A liposome containing a hydrophobic iodine compound represented by the following general formula (I) as a membrane component:in-line-formulae description="In-line Formulae" end="lead"?R1—CO2—R2in-line-formulae description="In-line Formulae" end="tail"?wherein R1represents a substituted or unsubstituted 2,3,5-triiodophenyl group or a substituted or unsubstituted 3,4,5-triiodophenyl group; and R2represents a hydrocarbon group having 10 or more carbon atoms, and an X-ray contrast medium, which comprises said liposome which is used for radiography of a vascular disease.

REFERENCES:
patent: 5550263 (1996-08-01), Hersl of et al.
patent: 5676928 (1997-10-01), Klaveness et al.
patent: 2 157 283 (1985-10-01), None
patent: WO 92/21384 (1992-12-01), None
patent: WO 01/82977 (2001-11-01), None
Radiolabeled Cholesteryl lopanoate\Acetylated Low Density Lipoprotein as a Potential Probe for Visualization of Early Atherosclerotic Lesions in Rabbits Pharmaceutical Research, vol. 16, No. 3 1999 p. 420-426.
XP-009003943—R .E. Counsell et al., Potential Organ- or Tumor-Imaging Agents. 21. Acyl-Labeled Esters of Cholesterol, J. Med. Chem. (1981), vol. 24, No. 1, pp. 5-6.
XP-009003944—R. H. Seevers et al.. Potential Organ- or Tumor-Imaging Agents. 22. Acyl-Labeled Cholesterol Esters, J. Med. Chem. (1982), vol. 25, No. 6, pp. 618-621.
XP-000985456—R. E. Counsell et al., Potential Tumor- or Organ-Imaging Agents XXIV: Chylomicron Remnants as Carriers for Hepatographic Agents, Journal of Pharmaceutical Sciences (1983), vol. 72, No. 8, pp. 898-901.
XP-002942252—W. Xiao et al., Radiolabeled Cholesteryl Iopanoate/Acetylated Low Density Lipoprotein as a Potential Probe for Visualization of Early Atherosclerotic Lesions in Rabbits, Pharmaceutical Research, NY (1999), vol. 16, No. 3, pp. 420-426.
XP-002228681—Douglas . A. Bakan et al., Physicochemical Characterization of a Synthetic Lipid Emulsion for Hepatocyte-Selective Delivery of Lipophilic Compounds: Application to Polyiodinated Triglycerides as Contrast Agents for Computed Tomography, Journal of Pharmaceutical Sciences, vol. 85, No. 9 (1996), pp. 908-914.
Marc A. Longino et al., Formulation of Polyiodinated Triglyceride Analogues in a Chylomicron Remnant-Like Liver-Selective Delivery Vehicle, Pharmaceutical Research, vol. 13, No. 6 (1996), pp. 875-879.

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