Liposome containing hydrophobic iodine compound

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – X-ray contrast imaging agent

Reexamination Certificate

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Details

C424S001110, C424S001450, C424S001650, C424S450000

Reexamination Certificate

active

07101532

ABSTRACT:
A liposome containing a hydrophobic iodine compound such as a 1,3,5-triiodobenzene derivative having at least one substituent containing 18 or more carbon atoms as a membrane component, and an X-ray contrast medium containing the liposome for use in radiography of a vascular disease and the like.

REFERENCES:
patent: 4192859 (1980-03-01), Mackaness et al.
patent: 5550263 (1996-08-01), Herslof et al.
patent: 2157283 (1985-10-01), None
XP-002301540—R. H. Seevers et al., “Potential Turmor- or Organ-Imaging Agents. 23. Sterol Esters of lopanoic Acid”, J. Med Chem. (1982), vol. 25., No. 12, pp. 1500-1503.
XP-002302389—Werner Krause, “Delivery of diagnostic agents in computed tomography” Elsevier Science B. V. (1999), pp. 159-173.
Supplementary European Search Report dated Nov. 5, 2004.

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