Liposome conjugates and diagnostic methods therewith

Details Liposome conjugates and diagnostic methods therewith Liposome conjugates and diagnostic methods therewith

1981-10-29

1986-07-01

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving antibody fragments

424 11, 436519, 436520, 436533, 436534, 436829, G01N 3353, G01N 33554, G01N 33555, G01N 33563

Patent

active

045980519

ABSTRACT:
A number of naturally occurring antibodies to human erythrocyte surface antigens are capable of combining with their specific antigens (for example, Rhesus factor), but are not capable of producing visible hemagglutination. Also, the sensitivity of many diagnostic methods, such as in human blood typing, depends upon cell agglutination.
The present invention provides liposome-protein conjugates, especially useful for hemagglutination assays, having an enhanced agglutination capacity with respect to antibody from

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