Liposome compositions

Details Liposome compositions Liposome compositions

2007-04-24

2007-04-24

Lukton, David (Department: 1654)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

C530S387100, C435S007500

Reexamination Certificate

active

11011266

ABSTRACT:
The present invention provides a non-covalent coupling method for the preparation of sterically stabilized lipsomes which may be used for targeted drug delivery, e.g., pegylated liposomes. The method simplifies the attachment of targeting vectors to sterically stabilized liposomes. The present invention also provides a liposome composition comprising a compound of the formulaand a compound of the formula Z-Y, wherein Z is any compound capable of binding to a cellular receptor, and X and Y are compounds which can interact with each other non-convalently, and wherein the substituents n, F1 and F2 are as provided in the specification.

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