Liposome composition for treating dry eye

Details Liposome composition for treating dry eye Liposome composition for treating dry eye

1986-10-21

1989-04-04

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424 11, 424450, 4284022, 436829, 514915, A61F 200, A61K 966, B01J 1302

Patent

active

048185370

ABSTRACT:
A liposome composition useful in the treatment of dry eye. The composition includes an aqueous suspension of liposomes whose lipid composition preferably includes about 70-85 mole percent of hydrogenated phosphatidylcholine, and 15-30 mole percent of benzyldimethylstearylammonium chloride. The suspension is stable on storage at room temperature for several months.

REFERENCES:
patent: 4201767 (1980-05-01), Fullerton et al.
patent: 4229360 (1980-10-01), Schneider et al.
patent: 4241046 (1980-12-01), Papahadjopoulos et al.
patent: 4350676 (1982-09-01), Laties et al.
patent: 4476140 (1984-10-01), Sears et al.
patent: 4565696 (1986-01-01), Heath et al.
patent: 4670185 (1987-06-01), Fujiwara et al.
Helene E. Schaeffer and David L. Krohn. Liposomes In Topical Drug Delivery. Invest. Ophthalmol. Vix. Sci, Feb. 1982 pp. 220-227.

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