Liposome-based topical vitamin D formulation

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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A61K 9127

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active

058340165

ABSTRACT:
A liposome-based formulation with good skin penetration of the effective substance, particularly calcitriol, is described. This formulation is well suited for the treatment of psoriasis.

REFERENCES:
patent: Re33107 (1989-11-01), Dikstein et al.
patent: 4708861 (1987-11-01), Popescu
patent: 5597575 (1997-01-01), Breitbarth
patent: 5616602 (1997-04-01), Tayler
patent: 5631394 (1997-05-01), Wei
International Search Report International Application No PCT/US97/04778 Dated Aug. 14, 1997.
Journal of Drug Targeting, vol. 2, No. 5, 1994, US, pp. 419-429, XP002037785, K. Prufer et al. Interaction of Liposomal Incorporated Vitamin D3-Analogues and Human Keratinocytes.

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