Liposomal-viral DNA complexes for treating disease

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435375, 435325, A61K 4800

Patent

active

061332437

ABSTRACT:
Methods and compositions for treating cancer consisting of viral DNA in association with liposomal material, the viral DNA substantially incapable of encoding a functional viral oncoprotein capable of binding to a functional tumor suppressor gene product in a neoplastic cell, and the viral DNA capable of replicating and forming infectious virus in neoplastic cells thereby killing the neoplastic cells and substantially incapable of replicating and forming infectious virus in non-neoplastic cells that have the tumor suppressor protein.

REFERENCES:
patent: 4925661 (1990-05-01), Huang
patent: 4957735 (1990-09-01), Huang
patent: 5043164 (1991-08-01), Huang
patent: 5677178 (1997-10-01), McCormick et al.
patent: 5801029 (1998-09-01), McCormick et al.
patent: 5846945 (1998-12-01), McCormick et al.
patent: 5856181 (1999-01-01), McCormick et al.
Marshall, E (1995) Science 269:1050-1055.
Miller et al (1995) FASEB. J. 9:190-199.
Felgner, P., Advanced Drug Delivery Reviews, vol. 5:163-187, 1990.
J. Zabner et al., `Cellular and Molecular Barriers to Gene Tranfer by a Cationic Lipid` Aug. 11, 1995 vol. 270 No. 32, pp 18997-19007 The American Society for Biochemistry and Molecular Biology, Inc.
W.-W. Zhang et al., `Generation and Identification of Recombinant Adenovirus by Lipsome-Mediated Transfection and PCR Analysis` vol. 15, No. 5 pp. 868-872 BioTechniques.
N. Miller and Richard Vile, `Targeted vectors for gene therapy` Feb. 1995 vol. 9 pp 190-199 The FASEB Journal.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Liposomal-viral DNA complexes for treating disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Liposomal-viral DNA complexes for treating disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Liposomal-viral DNA complexes for treating disease will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-468968

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.