Liposomal transfection of nucleic acids into animal cells

Details Liposomal transfection of nucleic acids into animal cells Liposomal transfection of nucleic acids into animal cells

1990-04-04

1994-01-18

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

435 6, 435 721, 435 725, 435 723, 436 71, 558169, 558172, 564282, 564291, 564463, A61K 3722, C07H 2102, C07H 2104

Patent

active

052798330

ABSTRACT:
A reagent for introducing a nucleic acid into an animal cell. The reagent comprises (a) a neutral lipid such as dioleoylphosphatidylethanolamine and (b) a cationic lipid selected from the group consisting of an ammonium salt such as dimethyldioctadecylammonium bromide or cetyldimethylethylammonium bromide, an amine such as stearylamine, and a benzethonium salt such as methylbenzethonium chloride

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