Liposomal delivery of AAV vectors

Details Liposomal delivery of AAV vectors Liposomal delivery of AAV vectors

1996-10-25

2000-07-11

Guzo, David

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

4353201, 4352351, 435 691, 435458, 536 232, 536 237, A61K 9127, A61K 9133, C12N 1586

Patent

active

060869135

ABSTRACT:
The invention provides compositions and methods for introducing a nucleic acid fragment into the genome of a cell. Suitable compositions comprise an expression vector having first and second inverted repeated sequences from an adeno associated virus, a rep gene from an adeno associated virus and the nucleic acid fragment. The expression vector is complexed with lipids.

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