Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1992-05-22
1994-05-17
Hollinden, Gary
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
436173, 1286534, 514492, 514502, 514836, 534 16, 564153, 564160, 556 50, 556 63, 556107, 556117, 556134, 556148, A61B 5055, C07C23300
Patent
active
053126173
ABSTRACT:
Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspending agents or other additives. The lipids may be in the form of liposomes, micelles or lipid emulsions. The contrast agents of the invention have particular use in magnetic resonance imaging of the liver, blood pool and reticuloendothelial system.
REFERENCES:
patent: 4647447 (1987-03-01), Gries et al.
patent: 4687658 (1987-08-01), Quay
patent: 4687659 (1987-08-01), Quay
patent: 4728575 (1988-03-01), Gamble et al.
patent: 4730066 (1988-03-01), White
patent: 4746507 (1988-05-01), Quay
patent: 4826673 (1989-05-01), Dean et al.
patent: 4885363 (1989-12-01), Tweedle et al.
patent: 4916246 (1990-04-01), Felder et al.
patent: 4933456 (1990-06-01), Rocklage et al.
patent: 4935518 (1990-06-01), Rocklage et al.
patent: 4952289 (1990-08-01), Ciccone et al.
patent: 4957939 (1990-09-01), Gries et al.
patent: 4963344 (1990-10-01), Gries et al.
patent: 4978763 (1990-12-01), Rocklage et al.
patent: 4980148 (1990-12-01), Dean
patent: 5078986 (1992-01-01), Bosworth et al.
Gries et al. Chem. Abs. 109(11):93624p (1988) from: DE 3633246.
Gries et al. Chem. Abs. 110(21):192267b (1988) from: DE 3633245.
Gries et al. Chem. Abs. 115(24):263459g (1991) from: EP 413405.
Modern Pharmaceutics, "Parenteral Products" pp. 505-507, Marcel Dekker, Inc. (1990).
Kabalka et al., Magnetic Resonance In Medicine, vol. 8, pp. 89-95 (1988).
Kabalka et al., Radiology, vol. 163, No. 1, pp. 255-258, (1987).
Navon et al., Magnetic Resonance In Medicine, vol. 3, pp. 876-880 (1986).
Schwendener et al., Investigative Radiology, vol. 25, pp. 922-932 (1990).
Unger et al., Magnetic Resonance In Medicine, vol. 22, pp. 304-308 (1991).
Andress, Jr., Prepr. Div. Pet. Chem., Am. Chem. Soc., vol. 18, No. 4, pp. 687-692 (1973).
Erne et al., Helv. Chim. Acta., vol. 63, No. 8, pp. 2264-2270 (1980).
Ulsperger et al., Journal fu praktische Chemie, vol. 4, pp. 195-212 Reihe, Band 27 (1965).
Shen Dekang
Unger Evan C.
LandOfFree
Liposoluble compounds useful as magnetic resonance imaging agent does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Liposoluble compounds useful as magnetic resonance imaging agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Liposoluble compounds useful as magnetic resonance imaging agent will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-875144