Liposoluble compounds useful as magnetic resonance imaging agent

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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436173, 1286534, 514492, 514502, 514836, 534 16, 564153, 564160, 556 50, 556 63, 556107, 556117, 556134, 556148, A61B 5055, C07C23300

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053126173

ABSTRACT:
Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspending agents or other additives. The lipids may be in the form of liposomes, micelles or lipid emulsions. The contrast agents of the invention have particular use in magnetic resonance imaging of the liver, blood pool and reticuloendothelial system.

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