Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1984-05-10
1986-10-28
Warren, Charles F.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 68, 4351722, 435240, 436514, 436518, 436536, 436548, 436811, 436815, 436542, 935104, 935110, 530837, G01N 33577, G01N 33535, C12N 500, C12N 1500
Patent
active
046198954
ABSTRACT:
Methods and compositions are provided for the detection of a particular low density lipoprotein which has been found to be a marker for patients suffering from type IV hypertriglyceridemia. A monoclonal antibody capable of specifically binding to a characteristic epitopic site on this LDL subspecies can be utilized in a wide variety of immunoassays.
Hybridoma cell line SPL.IVA5A1 was deposited at the American Type Culture Collection on Mar. 29, 1984, and granted accession no. HB 8535.
REFERENCES:
Teng, B. et al, Proc. Natl. Acad. Sci., USA, vol. 80(21), pp. 6662-6666 (1983).
Patton, J. G. et al, J. Immunol. Methods, vol. 55(2), pp. 193-203 (1982).
Milne, R. W. et al, Arteriosclerosis, vol. 3(1), pp. 23-30 (1-1983).
Milne, R. W. et al, FEBS Lett., vol. 146(1), pp. 97-100 (9-1982).
Milne, R. W. et al, J. Clin. Invest., vol. 68(1), pp. 111-117 (1981).
Mao, S. J. T. et al, Clin. Chem., vol. 29(11), pp. 1890-1897 (1983).
Curtiss, L. K., J. Clin. Invest., vol. 72(4), pp. 1427-1438 (1983).
Nelson, C. A., J. Lipid Research, vol. 25(8), pp. 821-830 (1984).
Patton, J. G. et al, Clin. Chem., vol. 29(11), pp. 1898-1903 (1983).
Tikkanen, M. J. et al, Arteriosclerosis, vol. 4(2), pp. 138-146 (3-1984).
Tikkanen, M. J. et al, J. Lipid Res., vol. 24(11), pp. 1494-1499 (1983).
Tikkanen, M. J. et al, J. Lipid Res., vol. 23, pp. 1032-1038 (1982).
Watt, T. S. et al, Proc. Natl. Acad. Sci. USA, vol. 80(1), pp. 124-128 (1983).
Krauss et al. (1980) Clin. Chim. Acta. 104:275-290 "Interrelationships Among Sungroups of Serum Lipoproteins in Normal Human Subjects".
Shen et al. (1981) J. Lipid Res. 22:236-244 "Heterogeneity of Serum Low Density Lipoproteins in Normal Human Subjects".
Lindgren et al. (1981) in: "AOCS Conference on Dietary Fats and Health", Perkins and Visek, eds., Chicago, Human Serum . . . and Analysis.
Krauss and Burke (1982) J. Lipid Res. 23:97-104 "Identification of Multiple Subclasses of Plasma Low Density Lipoproteins . . . Humans".
Maciejko et al. (1983) N. Eng. J. Med. 309:385-389 "Apolipoprotein A-I as a Marker of Angiographically Assessed Coronary-Artery Disease".
Blackburn (1983) N. Eng. J. Med. 309:426-428 "The Meaning of a New Marker for Coronary-Artery Disease".
Tikkanen et al. (1982) J. Lipid Res. 23:1032-1038 "Antigenic Mapping of Human Low Density Lipoprotein with Monoclonal Antibodies".
Marcel et al. (1982) J. Biol. Chem. 257:13165-13168 "Mapping of Antigenic Determinants of Human Apolipoprotein B . . . Density Lipoproteins".
Mao et al. (1982) Biochem. Biophys. Acta 713:365-374 "Immunochemical Properties of Human Low Density Lipoproteins as . . . Antibodies".
Cubicciotti Roger S.
Karu Alexander E.
Krauss Ronald M.
Moskowitz Margaret
The Regents of the University of California
Warren Charles F.
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