Lipopolysaccharide binding protein derivatives

Details Lipopolysaccharide binding protein derivatives Lipopolysaccharide binding protein derivatives

1994-06-17

1998-03-24

Jagannathan, Vasu S.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

4352402, 4352523, 4353201, 514 8, 530395, 536234, 536 235, A61K 3817, C07K 1900, C12N 1500, C12N 1509

Patent

active

057314152

ABSTRACT:
Disclosed are novel biologically active lipopolysaccharide binding protein (LBP) derivatives including LBP derivative hybrid proteins which are characterized by the ability to bind to and neutralize LPS and which lack the CD14-mediated immunostimulatory properties of holo-LBP.

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