Lipophilic ethers and/or esters of D-desosamine and their compos

Details Lipophilic ethers and/or esters of D-desosamine and their compos Lipophilic ethers and/or esters of D-desosamine and their compos

1989-12-06

1992-08-25

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 25, 514 42, 424DIG5, 536 72, 536 74, 536 172, 536 179, 536 552, 536115, 536116, 536119, 536120, A61K 3170, C07H 1700, C07H 506, C07H 1504

Patent

active

051419297

ABSTRACT:
Ethers and/or esters of D-desosamine having the formula ##STR1## wherein

REFERENCES:
patent: 2862921 (1958-12-01), Booth et al.
patent: 3923784 (1975-12-01), Kierstead et al.
patent: 4150220 (1979-04-01), Sciavolino
Chemical Abstracts, vol. 79, issued 1973, (Columbus Ohio, U.S.A.), P. Kurath et al., "C-8 Epimeric 8-Hydroxyerythromycins B" see p. 472, column 2, the Abstract No. 92539f Helv. Chim. Acta 1973, 56 (5), 1557-65 (Eng).
Chemical Abstracts, vol. 96, issued 1982, (Columbus Ohio, U.S.A.), H. Redlich et al., "Syntheses of some .beta.-Mycaminose Glycosides", see p. 647, column 1, the Abstract No. 69317h, Liebigs Ann. Chem. 1981, (7), 1223-33 (Ger).
Chemical Abstracts, vol. 110, No. 9, issued 1989, Feb. 27 (Columbus, Ohio, U.S.A.) K. Suzuki et al., "New Glycosidation Reaction 2, Preparation of 1-Fluoro-D-Desosamine Derivative and its Efficient Glycosidation by the use of C.sub.p2 HFCl.sub.2 --AgClO.sub.4 as the Activator" see page 698, column 1, the Abstract No. 75396h, Tetrahedron Lett. 1988, 29(29), 3571-4 (Eng).
Chemical Abstracts, vol. 113, issued 1990, (Columbus Ohio, U.S.A.) M. Delaforge et al. "In Vivo Effects of Erythromycin, Oleandomycin and Erythralosamine Derivatives on Hepatic Cytochrome P-450", see p. 15, column 2, the Abstract No. 164949u, Biochem. Pharmacol. 1990, 40(2), 223-8 (Eng).
Carbohydrate Research, vol. 1, No. 2, 1965, pp. 137-144, Celmer et al., "The alpha-L- and beta-D-Pyranoside Linkages in Oleandomycin".
Antimicrobial Agents and Chemotherapy, vol. 28, No. 1, Nov. 1985, pp. 630-633, Kibwage et al.: "Antibacterial Activities of Erythromycins A, B, C and D and some of their derivatives".
Chemical Abstracts, vol. 103, No. 7, Aug. 19, 1985, p. 16, No. 47853r Sartori et al.: "Some Erythromycin Derivatives are Strong Inducers in Rats of a Cytochrome P-450 Very similar to that Induced by 16 alpha-Prenenolone Carbonitrile".

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