Lipophilic benzothiophenes

Details Lipophilic benzothiophenes Lipophilic benzothiophenes

1996-09-04

1998-03-10

Clardy, S. Mark

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514324, 514422, 548525, 546202, A61K 3156, A61K 3144, A61K 31445, C07D33352

Patent

active

057261687

ABSTRACT:
The invention provides novel benzothiophenes of the formula (I): ##STR1## wherein R.sub.1 is N-pyrrolidinyl or N-piperidinyl;

REFERENCES:
patent: 4133814 (1979-01-01), Jones et al.
patent: 4418068 (1983-11-01), Jones
patent: 5210211 (1993-05-01), Hodges et al.
Haudenschild, Christian C., "Pathobiology of Restenosis After Angioplasty", American Journal of Medicine, 94, 40-44 (1993).
Wilensky, Robert L. et al., "Methods and Devices for Local Drug Delivery in Coronary and Peripheral Arteries", Trends Cardiovasc Med, 3, 163-170 (1993).
Waller, Bruce F. et al., "Morphologic Observations Late After Coronary Balloon Angioplasty: Mechanisms of Acute Injury and Relationship to Restenosis.sup.1 ", Radiology, 174, 961-967 (1990).

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