Lipophilic, aminohydrolase-activated prodrugs

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

536 276, 536 278, 536 2781, C07H 1916

Patent

active

054592569

ABSTRACT:
The present invention relates, in general, to prodrugs. In particular, the present invention relates to lipophilic, aminohydrolase-activated, anti-viral nucleoside prodrug compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds.

REFERENCES:
patent: 2928773 (1960-03-01), Klein
patent: 4704357 (1987-11-01), Mitsuya et al.
patent: 4711955 (1987-12-01), Ward et al.
patent: 4751221 (1988-06-01), Watanabe et al.
patent: 4788181 (1988-11-01), Driscoll et al.
patent: 4880782 (1989-11-01), Eckstein et al.
patent: 4882316 (1989-11-01), Lambert et al.
patent: 4886785 (1989-12-01), Lambert et al.
patent: 4908440 (1990-03-01), Sterzycki et al.
patent: 4963662 (1990-10-01), Matthes et al.
patent: 5106837 (1992-04-01), Carson et al.
Watanabe et al., J. Med. Chem., vol. 27, pp. 91-94 (1984).
Cheng et al., J. Biol. Chem., vol. 262, No. 5, pp. 2187-2189 (1987).
Lin et al., Biochem Pharmacol., vol. 36, No. 3, pp. 311-316 (1987).
Harada et al. J. Med. Chem., vol. 30, pp. 226-229 (1987).
Mikhailov et al., Bioorg. Khim., vol. 12, No. 5, pp. 626-632 (1986).
Herdewijn et al., J. Med. Chem., vol. 30, pp. 2131-2137, (1987).
Sandstrom et al., Drugs, vol. 34, pp. 372-390, 1987.
Mitsuya et al., Retroviruses in Human Lymphoma/Leukemia, Miwa et al. (EDS) Tokyo pp. 277-288 (1985).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Lipophilic, aminohydrolase-activated prodrugs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lipophilic, aminohydrolase-activated prodrugs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lipophilic, aminohydrolase-activated prodrugs will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-598549

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.