Lipopeptide derivatives

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Cyclic peptides

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A61K 3702, C07K 512, C07K 706

Patent

active

053860098

ABSTRACT:
The present invention is directed to water-soluble derivatives of antibiotic lipopeptides. The derivatives have good solubility properties in aqueous medium, rendering them more useful as therapeutic agents.

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Traver et al., Helv. Chim. Acta 62, 4, 1252-67 (1979).
Pache, W. et al., 13th International Congress Chemotherapy (1983), PS 4.8/3, Part 115, Abstract No. 10; also references in Ann. Reports in Med. Chem. 19, Sec. III, 130-131.

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