Lipoic acid in topical compositions

Details Lipoic acid in topical compositions Lipoic acid in topical compositions

1995-09-20

1998-01-20

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424 59, 424450, 514785, 514863, 514887, 514937, 514944, 514947, 514969, A61K 748, A61K 742

Patent

active

057098689

ABSTRACT:
In a method for the prevention and/or treatment of skin damage, particularly inflammation and aging, a composition containing lipoic acid and/or a lipoic acid derivative is topically applied to affected skin areas. A fat-soluble fatty acid ester of ascorbic acid such as palmityl ascorbate and/or tocotrienol is preferably applied with the lipoic acid or derivative in association with a dermatologically acceptable carrier.

REFERENCES:
Maitra, I., et al., Free Rad, Biol. Med. 18:823-829 (1995).
Merck Indes, 11th ed., 1989, Entry 9255 (p. 1469).

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