Lipisomes containing gas for ultrasound detection

Details Lipisomes containing gas for ultrasound detection Lipisomes containing gas for ultrasound detection

1983-06-20

1990-02-13

Warden, Robert J.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

424 4, 424 43, 424 44, 436829, 128653R, 128654, 2523153, A61K 4900, G01N 3100

Patent

active

049005405

ABSTRACT:
Phospholipid liposomes are provided having a lipid bilayer surrounding a confined composition which includes a gas or a gas precursor. The liposomes can be administered to a patient and can be detected in vivo by ultrasound techniques which permit organ imaging.

REFERENCES:
patent: 4192859 (1980-03-01), Mackaness et al.
patent: 4344929 (1982-08-01), Bonsen et al.
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4675310 (1987-06-01), Chapman et al.
MacNaughton et al., Biochim. Biophys. Acta 597 (1980), 193-198.
Gutknecht et al., Chemical Abstracts 87:34772q (1977).

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