Lipids containing omega-3 and omega-6 fatty acids

Details Lipids containing omega-3 and omega-6 fatty acids Lipids containing omega-3 and omega-6 fatty acids

2011-06-28

2011-06-28

Wax, Robert A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

C424S523000, C424S195170

Reexamination Certificate

active

07968112

ABSTRACT:
A lipid preparation including a glycerophospholipid or salt, conjugate and derivatives thereof, particularly phosphatidylserine (PS), phosphatidyicholine (PC), phosphatidylethanolamine (PE), phosphatidyl-inositol (PI), phosphatidylglycerol (PG) and phosphatidic acid (PA), and poly-unsaturated fatty acid (PUFA) acyl groups, particularly long-chain poly-unsaturated fatty acid (LC-PUFA) acyl groups such as omega-3 and/or omega-6 acyl groups, wherein said PUFA is covalently bound to said glycerophospholipid. The preparation possesses an improved bioactivity, and is useful in the treatment of various cognitive and mental conditions and disorders and for maintenance of normal functions of brain-related systems and processes.

REFERENCES:
patent: 5015483 (1991-05-01), Haynes et al.
patent: 5700668 (1997-12-01), De Ferra et al.
patent: 5750572 (1998-05-01), Bruzzese
patent: 5925669 (1999-07-01), Katz et al.
patent: 6005004 (1999-12-01), Katz et al.
patent: 6514973 (2003-02-01), Buchholz et al.
patent: 6541043 (2003-04-01), Lang
patent: 6645742 (2003-11-01), De Ferra et al.
patent: 2004/0120985 (2004-06-01), Geiss
patent: 2004/0234587 (2004-11-01), Sampalis
patent: 2005/0130937 (2005-06-01), Ben Dror
patent: 2006/0241080 (2006-10-01), Dror et al.
patent: 2007/0160659 (2007-07-01), Platt et al.
patent: 2008/0085319 (2008-04-01), Dror et al.
patent: 2009/0074857 (2009-03-01), Dror et al.
patent: 29 07 778 (1979-08-01), None
patent: 199 17 249 (2000-07-01), None
patent: 199 43 198 A 1 (2001-03-01), None
patent: 199 43 198 (2001-03-01), None
patent: 0209037 (1987-01-01), None
patent: 0275224 (1993-07-01), None
patent: 0275005 (1993-08-01), None
patent: 0 609 078 (1994-01-01), None
patent: 0 609 078 (1994-01-01), None
patent: 0819760 (1998-01-01), None
patent: 0922707 (1999-06-01), None
patent: 1213294 (2002-06-01), None
patent: 1417211 (2007-05-01), None
patent: 2088750 (1996-08-01), None
patent: 03188088 (1991-08-01), None
patent: 06256179 (1994-09-01), None
patent: 06279311 (1994-10-01), None
patent: 2001-122884 (2001-05-01), None
patent: 2001-354680 (2001-12-01), None
patent: 2002-241385 (2002-08-01), None
patent: WO 92/21335 (1992-12-01), None
patent: WO 96/37200 (1996-11-01), None
patent: WO 97/39759 (1997-10-01), None
patent: WO 00/23546 (2000-04-01), None
patent: WO 00/56869 (2000-09-01), None
patent: WO 01/82902 (2001-11-01), None
patent: WO 01/84961 (2001-11-01), None
patent: WO 02/102394 (2002-12-01), None
patent: WO 03/088949 (2003-10-01), None
patent: WO 2004/049907 (2004-06-01), None
patent: WO 2005/038037 (2005-04-01), None
Marabella A. Alhambra MD, et. al., EEG Biofeedback: A New Treatment Option For ADD/ADHD, Journal of Neurotherapy, 1995, pp. 39-43, vol. 1, No. 2.
Gwendolyn Barcelo-Coblijn et. al., Modification by docosahexaenoic acid of age-induced alterations in gene expression and molecular composition of rat brain phospholipids, PNAS, Sep. 30, 2003, pp. 11321-11326, vol. 100, No. 20, The National Academy of Science of the USA.
D. Benton et. al., The Influence of Phosphatidylserine Supplementation on Mood and Heart Rate when Faced with an Acute Stressor, Nutritional Neuroscience, 2001, pp. 169-178, vol. 4.
Nicole Brossard et. al., Human plasma albumin transports [13C]docosahexaenoic acid in two lipid forms to blood cells, Journal of Lipid Research, 1997, pp. 1571-1582, vol. 38.
John R. Burgess et. al., Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder, Am. J. Clin. Nutri., 2000, pp. 327S-330S, vol. 71.
Julie A. Conquer et. al., Fatty Acid Analysis of Blood Plasma of Patients with Alzheimer's Disease, Other Types of Dementia, and Cognitive Impairment, Lipids, 2000, pp. 1305-1312, vol. 35, No. 12.
Gordon B. Forbes, Clinical Utility of the Test of Variables of Attention (TOVA) in the Diagnosis of Attention-Deficit/Hyperactivity Disorder, Journal of Clinical Psychology, 1998, pp. 461-476, vol. 54, No. 4, John Wiley & Sons, Inc.
Charles H. Goyette et. al., Normative Data on Revised Conners Parent and Teacher Rating Scales, Journal of Abnormal Child Psychology, 1978, pp. 221-236, vol. 6, No. 2.
Pnina Green et. al., Modulation of Fetal Rat Brain and Liver Phospholipid Content by Intraamniotic Ethyl Docosahexaenoate Administration, Journal of Neurochemistry, 1995, pp. 2555-2560, vol. 65, No. 6, Lippincott-Raven Publishers, Philadelphia.
Lawrence M. Greenberg et. al., Developmental Normative Data on The Test of Variables of Attention (T.O.V.A), J. Child Psychol. Psychiatry, 1993, pp. 1019-1030, vol. 34, No. 6.
Genevieve S. Young, et. al., Effect of randomized supplementation with high dose olive, flax or fish oil on serum phospholipid fatty acid levels in adults with attention deficit hyperactivity disorder, Reprod. Nutr. Dev., 2005, pp. 549-558, vol. 45.
Tomohito Hamazaki et. al., Administration of Docosahexaenoic Acid Influences Behavior and Plasma Catecholamine Levels at Times of Psychological Stress, Lipids, 1999, pp. S33-S37, vol. 34, Supplement.
Barbara V. Howards, PhD. et. al., Low-Fat Dietary Pattern and Risk of Cardiovascular Disease, JAMA, Feb. 8, 2006, pp. 655-666, vol. 295, No. 6, American Medical Association.
FDA/ Center for Food Safety & Applied Nutrition, Final Decision Letter written by Christine L. Taylor, PhD., Phosphatidylserine and Cognitive Dysfunction and Dementia (Qualified Health Claim: Final Decision Letter), Office of Nutrition Products, Labeling and Dietary Supplements, U.S. Food & Drug Administration, May 13, 2003.
Miho Itomura et. al., The effect of fish oil on physical aggression in schoolchildren—a randomized, double-blind, placebo-controlled trial, Journal of Nutritional Biochemistry, 2005, pp. 163-171, vol. 16, Elsevier Inc.
B. L. Jorissen et. al., The Influence of Soy-derived Phosphatidylserine on Cognition in Age-Associated Memory Impairment, Nutritional Neuroscience, 2001, pp. 121-134, vol. 4.
Dominique Lemaitre-Delaunay, et. al., Blood compartmental metabolism of docosahexaenoic acid (DHA) in humans after ingestion of a single dose of [13C]DHA in phosphatidylcholine, Journal of Lipid Research, 1999, pp. 1867-1874, vol. 40.
Ann-Marie Lyberg, et. al., Monitoring the Oxidation of Docosahexaenoic Acid in Lipis, Lipids, 2005, pp. 969-979, vol. 40, No. 9.
Mark A. McDaniel, et. al., “Brain-Specific” Nutrients: A Memory Cure?, Psychological Science in the Public Interest, May 2002, pp. 12-38, vol. 3, No. 1, American Psychological Society.
Thomas A. Rugino, MD, et. al., Effects of Modafinil in Children With Attention-Deficit/Hyperactivity Disorder: An Open-Label Study, J. Am. Acad. Child Adolesc. Psychiatry, Feb. 2001, pp. 230-235, vol. 40, No. 2.
Laura Stevens, et. al., EFA Supplementation in Children with Inattention, Hyperactivity, and Other Disruptive Behaviors, Lipids, 2003, pp. 1007-1021, vol. 38, No. 10.
Tsakiris, S. (1984) Z Naturforsch {Cl, 39 (11-12); 1196-8.
Kidd, Phosphatidylserine: Membrane Nutrient for Memory. A Clinical and Mechanistic Assessment, 1996, Alternative Medicine Review, vol. 1, No. 2, pp. 70-84.
Bligh and Dyer, (1959) Can. J. Biochem. Physiol. 37, 911-917.
Sakai M. (1996) Nutr Sci Vitaminol. (Tokyo) 42(2-1):47-54.
Carrie et al., (2000) J. Lipid Res. 41, 465-472.
Yabuuchi et al. (1968) J. Lipid Res. 9(1):65-7.
Wijendran et al (2002) Pediatr. Res. 51:265-272.
Lytle et al. (1992) Nutr Cancel.: 17(2):187-94.
Suzuki et al. (2000) Jpn. J. Pharrnacol. 84, 86-8.
Drago et al. (1981) Neurobiol Aging. 2(3):209-13.
Voigt et al. (2001) J. Pediatr.; 139(2):189-96.
Zanotti A. et al. (1986) Psychopharmacology (Berl). 90(2):274-5.
Pearce et al. (1998) Nature 396: 75-77.
Kolanowski et al. (2001) Int. J. Food Sci Nutr.: 52(6):469-76.
Stubberfield et al. (1999) J. Paediatr Child Health; 35:450-3.
Williams et al. (1980) J. Neurochem.; 35, 266-269.
Claro F. et al. (1999) Physiol Behan. 67(4):551-4.
Chalon, et al (1998) JNutr.; 128(12):2512-9.
Suzuki et al (2001) J. Nut. 131:2951-6.
Song et al., Enhanced level of n-3 fatty acid in membrane phospholipids induces lipid peroxidation in rats fed dietary docosahexaenoic acid oil, 2001, Atherosclerosis. 155, pp. 9-18.
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