Lipidic furans useful for skin therapeutics

Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Skin cosmetic coating

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514461, A61K 3134

Patent

active

054684900

ABSTRACT:
A composition of matter useful for enhancing the metabolism of the skin and mucosal tissue and thereby improving its health and appearance. The composition of matter has the furan (2)--R, wherein R is a straight C.sub.9--36 alkyl chain, having the formula CH.sub.3 --(CH.sub.2).sub.n --(CH.sub.2).sub.n CH.sub.3, (n=8 to 35). R can also be a straight unsaturated C.sub.9-36 alkenyl chain with a single double bond, of the formula --(CH.sub.2).sub.n --CH.dbd.CH--(CH.sub.2).sub.m --CH.sub.3, wherein n and m.noteq.0 and n+m32 6 to 33. R can be a straight unsaturated C.sub.9-36 chain, containing two to six double bonds, with the formula CH.sub.3 --(CH.sub.2).sub.m --(CH.dbd.CH).sub.x --(CH.sub.2).sub.n --, wherein m, x and n .noteq.0, m+2x+n=8 to 35. R can likewise be a straight unsaturated C.sub.9-36 chain containing one to six double bonds and one triple bond, having the formula CH.sub.3 --(CH.sub.2).sub.m --C.tbd.C--(CH.dbd. CH--CH.sub.2).sub.x --, wherein m and x.noteq.0 and m+3x=6 to 33. R may be a straight unsaturated chain C.sub.9--36 containing one to six double bonds and two to six triple bonds, having the structure CH.sub.3 --(CH.sub.2).sub.m --(C.tbd.C--CH.sub.2).sub.y --(CH.dbd.CH--CH.sub.2).sub.x --(CH.sub.2).sub.n --, wherein m, y, x and n.noteq.0 and m+3y+3x+n=8 to 35.

REFERENCES:
APS Abs 55-20739 (Feb. 14, 1980) Takemoto et al.
APS Ab 01-186815 (Jul. 26, 1989) Yamada.
APS Abs 56-113760 (Sep. 7, 1981) Onnishi et al.
Derwent Abs 89-052037 (J64003192) Watanabe.
APS Abs 62-158206 (Jul. 14, 1987) Svetsugu et al.
APS Abs 01-40412 (Feb. 10, 1989) Kamisaka et al.
APS Abs 01-132511 (May 25, 1989) Miyazaki.
APS Abs 58-41813 (Mar. 11, 1983) Awamura.

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