Lipid vesicles prepared in a monophase

Details Lipid vesicles prepared in a monophase Lipid vesicles prepared in a monophase

1983-08-08

1986-05-13

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 436829, 4284022, A61K 4300, A61K 4900

Patent

active

045885788

ABSTRACT:
A process for the preparation in a monophasic solvent system of a new type of lipid vesicles, called monophasic lipid vesicles (MPVs). MPVs can be made to encapsulate one or more bioactive agents. MPVs are stable during storage and can be used in vivo in the treatment of disease.

REFERENCES:
patent: 4224179 (1980-09-01), Schneider
patent: 4235871 (1980-11-01), Papahadjopolous
patent: 4394372 (1983-07-01), Taylor
Bangham et al., J. Mol. Biol. 13: 238-252 (1965).
Papahadjopolous and Miller, Biochim. Biophys. Acta 135: 624-638 (1967).
Deamer and Bangham, Biochim. Biophys. Acta 413: 629-634 (1976).
Batzri and Korn, Biochim. Biophys. Acta 298: 1015-1019 (1973).
Szoka and Papahadjopolous, Proc. Nat. Acad. Sci. USA 75: 4194-4198 (1978).

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