Lipid vesicles formed with alkylammonium fatty acid salts

Details Lipid vesicles formed with alkylammonium fatty acid salts Lipid vesicles formed with alkylammonium fatty acid salts

1999-02-22

2000-06-06

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424401, 424417, 424 701, 424 943, 264 41, 264 43, 514880, 514881, 935 54, A61K 9127, A61K 9133, A61K 700

Patent

active

060715359

ABSTRACT:
The present invention provides for liposomes formed with alkylammonium fatty acid salts, and methods for manufacturing same. The liposomes of the invention may deliver entrapped load material or materials at the occurrence of a preset triggering condition. Preferred liposomes of the invention are cationic liposomes. The preferred liposomes of the invention are formed with alkylammonium fatty acid salts, e.g., trialkylammonium fatty acid salts of long chain amides. The liposomes of the invention are used to encapsulate both hydrophobic and hydrophilic load materials. The liposomes formed accordingly are capable of delivering their loads upon the occurrence of a trigger or control condition.

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