Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1996-01-31
1999-02-23
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
264 41, 264 43, A61K 9127
Patent
active
058741054
ABSTRACT:
A liposome for use in encapsulating both hydrophobic and hydrophilic substances (i.e., a "payload"),is disclosed which is capable of delivering their load upon the occurrence of a trigger or control condition. The liposomes are formed to stably encapsulate a particular active agent to form a delivery vehicle for the agent. The liposomes of the delivery vehicle are stable in a particular environment but become unstable or permeable if passed from the stable environment (e.g., characteristic of a particular pH and/or temperature and/or ionic strength) to a changed or unstable environment, thereby delivering their payload.
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Hayward James A.
Vichroski Thomas J.
Watkins David C.
Collaborative Laboratories, Inc.
Kishore Gollamudi S.
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