Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1993-03-03
1995-03-07
Kishore, G. S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
264 41, 264 43, 264 433, 4284022, A61K 9127
Patent
active
053956192
ABSTRACT:
A lipid-polymer conjugate for use in forming long-circulating liposomes is disclosed. The conjugate includes a vesicle-forming lipid having covalently attached to its polar head group, one of the polymers: polyvinylpyrrolidone, polyvinylmethylether, polyhydroxypropyl methacrylate, polyhydroxypropylmethacrylamide, polyhydroxyethyl acrylate, polymethacrylamide, polydimethylacrylamide, polymethyloxazoline, polyethyloxazoline, polyhydroxyethyloxazoline, polyhydroxypropyloxazoline, or polyaspartamide. A method for preparing liposomes containing the lipid-polymer conjugate is also disclosed.
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Lasic Danilo D.
Martin Francis J.
Woodle Martin C.
Zalipsky Samuel
Dehlinger Peter J.
Kishore G. S.
Liposome Technology, Inc.
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