Lipid membrane structures

Details Lipid membrane structures Lipid membrane structures

1991-03-04

1992-08-25

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 264 43, 264 46, 4284022, 514 2, 436829, A61K 9127

Patent

active

051417510

ABSTRACT:
Lipid membrane structures containing, in the lipid membrane thereof, a compound represented by formula (I): ##STR1## wherein R.sub.1 represents a hydrogen atom or a fatty acid residue; R.sub.2 represents a hydrogen atom or an acyclic hydrocarbon residue; R.sub.3 represents an amino group, a guanidino group or an amidino group; and n represents an integer of from 1 to 6; provided that R.sub.1 and R.sub.2 do not represent hydrogen atoms at the same time, or a salt thereof. The lipid membrane structures exhibit excellent specific affinity for tumor cells and can be delivered preferentially to tumor cells.

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patent: 4897308 (1990-01-01), Vanlerberghe et al.
patent: 4917951 (1990-04-01), Wallach
patent: 4983397 (1991-01-01), Schroit et al.
patent: 5021200 (1991-06-01), Vanlerberghe et al.

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