Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1979-09-13
1983-03-22
Lovering, Richard D.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
252316, 424 35, 424 85, 424178, 424DIG6, A61K 4300, A01N 2528, A61K 962, B01J 1302
Patent
active
043775675
ABSTRACT:
Lipid Membrane Structures comprising Digalactosyl Diglyceride target the liver of humans and lower animals and are used to carry drugs to that organ, preferentially. Digalactosyl Diglyceride LMS containing insulin provide an effective means for treating diabetes mellitus. Digalactosyl Diglyceride LMS containing interferon are used to treat viral hepatitis.
REFERENCES:
patent: 3937668 (1976-08-01), Zolle
patent: 3957971 (1976-11-01), Oleniacz
Endocrinology 90, 12 (1972)-Canfield, Kay and West.
Immunochemistry, 11, 475-481 (1974).
Lunny and Ashwell, Proc. Natl. Acad, Sci. USA, 73 341-343 (1976).
Mauk and Gamble, Proc. Natl. Acad. Sci. USA, 76, 356-369 (1979).
J. Lab. Clin. Med. 83 (4), 640-647 (1974).
FEBS Letters 62, 1, 60-63 (1976), Patel, et al.
Proceedings of the Society for Experimental Biol. and Medicine 146, 1173-1176 (1974).
Biochimica et Biophysica Acta 311, 513-544 (1974).
Gebicki, et al., Chem. Phys. Lipids 16 (2), 142-160 (1976).
New England Journal of Medicine, 9/23/76, pp. 704-710 and 9/30/76, pp. 765-770.
Journal of Lipid Research 9, 310-318 (1968).
Laboratory Investigation 34, No. 3, 276, et seq. (1976).
Proccedings of the National Academy of Sciences 71, No. 9, 3487-3491 (1974).
Life Sciences 17, 715-724.
Chem. Pharm. Bull. 23 (10) 2218-2222 (1975).
Science News, vol. 114, No. 4, (7/22/78).
Gregoriadis, Biochemical Society Transactions, vol. 3 (1975), p. 613.
Gregoriadis et al.: "Drug-Carrier Potential of Liposomes in Cancer Chemotherapy", The Lancet, Jun. 29, 1974, pp. 1313-1316.
Shipley et al.: "The Phase Behavior of Monogalactosyl, Digalactosyl, and Sulphoquinovosyl Diglycerides", Biochimica et Biophysica Acta", 311 (1973), 531-544.
Gregoriadis: "The Carrier Potential of Liposomes in Biology and Medicine", New England Journal of Medicine, Sep. 23, 1976, pp. 704-710.
Roerdink et al.: Biochimica et Biophysica Acta, 677 (1981), pp. 79-89.
Goldstein Steven J.
Lovering Richard D.
Schaeffer Jack D.
The Procter & Gamble & Company
Yetter Jerry J.
LandOfFree
Lipid membrane drug delivery does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Lipid membrane drug delivery, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lipid membrane drug delivery will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1869138