Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1984-03-20
1986-09-09
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
264 41, 264 432, 424 9, 424 22, 424 31, 4284022, 435 1, A61K 4300, A61K 4900
Patent
active
046108688
ABSTRACT:
Lipid matrix carriers are described which provide for the sustained release of bioactive agents in vivo or in vitro. The properties of the lipid matrix carriers of the present invention include high entrapment efficiencies; release of entrapped compounds in their active form; biodegradability and avoidance of vascular occlusion in vivo; and avoidance of sequestration of the bioactive agent in the liver and spleen.
REFERENCES:
patent: 3159545 (1964-12-01), Kidwell et al.
patent: 3159600 (1965-04-01), Brockett
patent: 3993754 (1976-11-01), Rahman et al.
patent: 4010038 (1977-03-01), Iwaski et al.
patent: 4145410 (1979-03-01), Sears
patent: 4224179 (1980-09-01), Schneider
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4298594 (1981-11-01), Sears
patent: 4310506 (1982-01-01), Baldeschwieler et al.
patent: 4317743 (1982-03-01), Chang
patent: 4349529 (1982-09-01), Morcos et al.
patent: 4356167 (1982-10-01), Kelly
patent: 4377567 (1983-03-01), Geho
patent: 4404183 (1983-09-01), Kawata et al.
patent: 4434153 (1984-02-01), Urquhart et al.
patent: 4460560 (1984-07-01), Tokes et al.
Bligh and Dyer, Can. J. Biochem. Physiol., 37:911, (1959).
Gregordiadis, G. et al., eds. in Targeting of Drugs, 268-272, Plenum Press, New York, 1982.
Gregordiadis, New England Med., 295: 704, (1976).
Ostro et al., in Liposomes and Immunobiology, Elsevier North Holland, Inc., eds. B. Tom and H. Six, 225-239, (1980).
Schroeder, Proceedings of the Controlled Release Society Meeting, San Francisco, Jul. 1983.
Fountain Michael W.
Kearns John J.
Popescu Mircea C.
Weiner Alan L.
Weiss Steven J.
Nucker Christine M.
The Liposome Company Inc.
LandOfFree
Lipid matrix carriers for use in drug delivery systems does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Lipid matrix carriers for use in drug delivery systems, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lipid matrix carriers for use in drug delivery systems will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1014816