Lipid emulsions in the treatment of systemic poisoning

Details Lipid emulsions in the treatment of systemic poisoning Lipid emulsions in the treatment of systemic poisoning

2007-08-28

2007-08-28

Kishore, Gollamudi S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

C424S400000, C514S937000, C514S938000, C514S943000

Reexamination Certificate

active

09622816

ABSTRACT:
Lipid emulsion compositions and methods of using such composition via intravenous infusion to reduce the bioavailability and toxicity of poisonous agents in the bloodstream.

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Cave et al. (2005), “Intralipid ameliorates thiopentone induced respiratory depression in rats: Investigative pilot study,” Emergency Medicine Australasia 17:180-183.
Goor and Goor (2003), “Letter to the editor: Has the silver bullet been found?” Regional Anesthesia and Pain Medicine 29(1):73-74.
Groban and Butterworth (2003), “Lipid reversal of bupivacaine toxicity: Has the silver bullet been identified?” Regional Anesthesia and Pain Medicine 28(3):167-169.
Krieglstein et al. (1974), “Influence of emulsified fat on chlorpromazine availability in rat blood,” Experientia 30:924-926.
Weinberg (2003), “Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity,” Regional Anesthesia and Pain Medicine 28(3):198-202.
Weinberg (2003), “Letter to the editor: Reply to Drs. Goor, Groban, and Butterworth—Lipid Rescue: Caveats and Recommendations for the ‘silver bullet’,” Regional Anesthesia and Pain Medicine 29(1):74-75.

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