Lipid-dispersed solution and process for producing the same

Details Lipid-dispersed solution and process for producing the same Lipid-dispersed solution and process for producing the same

1996-05-02

1998-06-02

Lovering, Richard D.

Compositions

Preservative agents

Anti-corrosion

252311, 2524081, 436 13, B01J 1300, C12Q 160

Patent

active

057594457

ABSTRACT:
There is disclosed an aqueous dispersed solution as a standard solution for determining lipid levels, having a dispersion form and a particle size, which are similar to those of serum lipids. A lipid-dispersed solution is obtained by evaporating an organic solvent from a mixture prepared by adding cholesterol, a phospholipid, a bile acid or bile acid salt, and a neutral lipid and/or a cholesterol ester in the organic solvent, swelling the resultant thin-film like mixture with water or buffer heated at a temperature higher than a phase transition temperature of the lecithin, and then dispersing the solution by a physical shear force. There can be easily obtained a solution having a cholesterol concentration of about less than 1,000 mg/dl, which is extremely stable and can be stored for a long period of time.

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patent: 4343897 (1982-08-01), Neumann et al.

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