Lipid containing formulations

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

Reexamination Certificate

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C514S04400A, C514S785000

Reexamination Certificate

active

08034376

ABSTRACT:
Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described.

REFERENCES:
patent: 5679852 (1997-10-01), Platzek et al.
patent: 2005/0064595 (2005-03-01), MacLachlan et al.
patent: 2006/0211642 (2006-09-01), McSwiggen et al.
patent: WO96/26179 (1996-08-01), None
patent: 2005/026372 (2005-03-01), None
patent: 2006138380 (2006-12-01), None
patent: WO 2006/138380 (2006-12-01), None
Akinc et al. “A combinatorial library of lipid-like materials for delivery of RNAi therapeutics” Nat. Biotech. 26:561-569 (2008).
Braun et al. “Structure/Function Relationships of Polyamidoamine/DNA Dendrimers as Gene Delivery Vehicles” J. Pharmaceutical Sciences 94(2):423-436 (2005).
Pedroso De Lima, et al. “Cationic Liposomes for Gene Delivery: From Biophysics to Biological Applications” Curr. Med. Chem. 10:1221-1231 (2003).
Westerberg et al. “Synthesis of Novel Bifunctional Chelators and Their Use in Preparing Monoclonal Antibody Conjugates for Tumor Targeting” J. Med. Chem. 32: 236-243 (1989).
European Search Report dated Nov. 10, 2010 from European Application No. 07853756.

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