Lipid-based metal sensor

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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540474, 422 8208, C07C22934, C07D25700

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active

056167903

ABSTRACT:
An fluorescent metal-chelating amphiphile having the structure: ##STR1## wherein A is a hydrophobic fluorophore, X and Y are aliphatic hydrocarbons having from 9 to 25 carbon atoms, B is a hydrophilic spacer, C is a metal chelator, and L is either an ether or ester linkage. The fluorescent metal-chelating amphiphile is combined with a matrix lipid to form lipid-based sensors which provide fluorometric detection of metal ions in liquids.

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