Lipid-based drug delivery systems against parasitic infections

Details Lipid-based drug delivery systems against parasitic infections Lipid-based drug delivery systems against parasitic infections

2007-01-23

2007-01-23

Tran, S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

C424S001210, C424S009321, C424S009510

Reexamination Certificate

active

10239527

ABSTRACT:
The present invention is directed to a lipid-based delivery system for administration of an active drug substance selected from lysolipid derivatives which are particularly useful in the treatment or detection of parasitic infections, especially parasitic infections which cause an elevated PLA2level in the infected mammal. Preferred parasitic infections are infections wherein the life cycle of the parasite involves the liver and/or spleen of the infected organism.

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Hart, D. et al., Chemical Abstracts, vol. 130, No. 25, Jun. 21, 1999.
Xia, J. et al., Tetrahedron: Asymmetrie, vol. 8, No. 18, Sep. 25, 1997, pp. 3131-3142.

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