Lipase variants

Details Lipase variants Lipase variants

2008-01-01

2008-01-01

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

C435S136000, C435S198000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07314739

ABSTRACT:
The invention relates to a lipase variant which can be prepared by carrying out, on the amino acid sequence of a starting lipase selected from the lipase homologous family I.1 or I.2, at least one amino acid substitution in those positions which correspond to the positions 17, 29, 30, 52, 86, 117, 122, 160, 163, 167, 265, 266, 286, 289 in the prototype lipase sequence SEQ ID NO: 1.

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Kim, M.H., et al., “Substitution of Glycine 275 by Glutamate (G275E) in Lipase ofBacillus stearothermophilusAffects Its Catalytic Activity and Enantio- and Chain Length Specificity”, J. Microbiol. Biotechnol. (2000), vol. 10, No. 5, pp. 764-769.

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