Lipase substrates

Details Lipase substrates Lipase substrates

1986-05-01

1989-07-11

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

260405, 544104, 558251, 558255, 560146, 560171, 548407, 549 11, 549 29, C07D26538

Patent

active

048473766

ABSTRACT:
The present invention provides a lipase substrate of the general formula: ##STR1## wherein A is an alkylene or alkenylene radical containing up to 16 carbon atoms, R and R.sub.1, which can be the same or different, each signify an alkyl, alkenyl or acyl radical containing up to 20 carbon atoms or an optionally alkyl-substituted aryl or aralkyl radical containing up to 8 carbon atoms in the alkyl moiety and wherein one of R and R.sub.1 can also be a hydrogen atom, X is the residue of an aromatic hydroxy or thiol compound, and each Y and Z, independently from each other, is --S-- or --O--, Z also --CH.sub.2 --.
The present invention also provides a process and a reagent for the optical determination of lipase.

REFERENCES:
patent: 4667032 (1987-05-01), Lau et al.

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