Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-09-05
2006-09-05
Witz, Jean C. (Department: 1651)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S640000
Reexamination Certificate
active
07101889
ABSTRACT:
The invention relates to compositions for treating dandruff comprising compounds that are non-polymeric and/or have a weight average molecular weight of less than about 1000. These compounds, when used at a concentration of about 0.001% or less, inhibit the activity of anyMalassezia globosalipase by at least 50%. The invention also relates to the use of these compounds for inhibiting lipase activity.
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George Kokotos, Robert Verger, and Antonia Chiou; “Synthesis of 2-Oxo Amide Triacylglycerol Analogues and Study of Their Inhibition Effect on Pancreatic and Gastric Lipases”;Chem. Eur. J.; pp. 4211-4217; vol. 6 No. 22; Wiley-VCH Verlag GmbH, D-69451 Weinheim, 2000.
A.K. Gupta, Y. Kohli, A.Li, J. Faergemann, and R.C. Summberbell; “In vitro susceptibility of the severn Malassezia species to ketoconazole, voriconazole, itraconazole and terbinafine”;British Journal of Dermatology2000 vol. 142 pp. 758-765; 2000 Britich Association of Dermatologists.
James G. Weeks, PH.D.; Leslie McCarty, PH.D.; Thomas Black, B.S.; & James E. Fulton, Jr., M.D., Ph.D.; “The Inability of a Bacterial Lipase Inhibitor to Control Acne Vulgaris”,The Journal of Investigative Dermatology; Aug. 1977; vol. 69 Issue 2; The Williams & Wilkins Company in the United States.
Degenhardt Charles Raymond
Eickhoff David Joseph
Gale Celeste Dawn
Garrett Garry Steven
Kaczvinsky, Jr. Joseph Robert
James Melody A.
Peebles Brent M.
The Procter & Gamble
Witz Jean C.
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