Linking compounds useful for coupling carbohydrates to amine-con

Details Linking compounds useful for coupling carbohydrates to amine-con Linking compounds useful for coupling carbohydrates to amine-con

1998-10-30

1999-09-14

Mosley, Terressa

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

From carboxylic acid or derivative thereof

5283393, 525 541, C08G 6926

Patent

active

059524545

ABSTRACT:
The present invention provides a method to couple a glycosyl donor to an amine-containing carrier or substrate material using as a spacer a compound of the general formula I: ##STR1## in which n and m are each independently an integer of from 1 to 12, R.sub.1 and R.sub.2 are each independently H, lower alkyl, a hydroxyl group, or a substituent which does not interfere with the linking reactions, R.sub.4 and R.sub.5 are each independently H, lower alkyl, a hydroxyl group, or a substituent which does not interfere with the linking reactions, R.sub.3 and R'.sub.3 are each independently an optionally substituted lower alkyl or R.sub.3 and R'.sub.3 can be joined to form an optionally substituted cyclic moiety having from 2 to 5 carbon atoms.

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patent: 5254676 (1993-10-01), Sabesan
patent: 5424297 (1995-06-01), Rubio et al.

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