Linkers for the synthesis of multiple oligonucleotides in seriat

Details Linkers for the synthesis of multiple oligonucleotides in seriat Linkers for the synthesis of multiple oligonucleotides in seriat

1993-04-05

1995-02-28

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2531, 536 2533, 536 2534, 558199, C07H 2100

Patent

active

053938771

ABSTRACT:
A method for the synthesis of a plurality of oligonucleotides comprising the steps of

REFERENCES:
Agarwal et al., "Studies on Polynucleotides. CXLIII. A Rapid and Convenient Method for the Synthesis of Deoxyribooligonucleotides Carrying 5'-Phosphate End Groups Using a New Protecting Group," J. Am. Chem. Soc., 98(5), 1065-1072 (1976).
Brandstetter et al., "Neue Polymer-Schutzgruppe in der Oligonucleotidesyntheses, 2-hydroxyathylphenylthioather von Polyathyleneglykol," Tett. Lett., 1974(31), 2705-2708.
Ikehara et al., "The Synthesis of Polynucleotides," Adv. Carbohydrate Chem. Biochem., 36, 135-213 (1979): only pp. 135 and 204-213 supplied.

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