Linkers for anchoring targeting ligands

Details Linkers for anchoring targeting ligands Linkers for anchoring targeting ligands

2011-08-16

2011-08-16

Hartley, Michael G (Department: 1618)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

C424S001110, C424S001210, C424S001650, C424S009360, C424S812000, C514S709000

Reexamination Certificate

active

07998462

ABSTRACT:
An improved linker which lacks chiral centers between a hydrophobic anchor for coupling to lipid-based particles and a targeting agent has suitable hydrophobic/hydrophilic properties for use in vivo.

REFERENCES:
patent: 6332770 (2001-12-01), Oueslati et al.
patent: 6511649 (2003-01-01), Harris et al.
patent: 2004/0013720 (2004-01-01), Ellens et al.
patent: 2009/0317475 (2009-12-01), Beardsley et al.
patent: WO-03/062198 (2003-07-01), None
International Search Report for PCT/US07/81540, mailed on Aug. 5, 2008, 3 pages.
Written Opinion of the International Searching Authority for PCT/US07/81540, mailed on Aug. 5, 2008, 6 pages.

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