Lightening compositions and methods of use

Details Lightening compositions and methods of use Lightening compositions and methods of use

2006-03-21

2006-03-21

Leith, Patricia (Department: 1655)

Drug, bio-affecting and body treating compositions

Live hair or scalp treating compositions

Permanent waving or straightening

C424S401000, C424S062000, C424S063000, C424S064000, C424S725000

Reexamination Certificate

active

07014844

ABSTRACT:
There is provided a topical lightening composition having carboxylmethyl cysteamine as a melanin synthesis-regulating agent and a cosmetically acceptable vehicle. Also, there is provided a topical lightening composition having N, N, S (tris) carboxylmethyl cysteamine and a cosmetically acceptable vehicle. In addition, there is provided a topical lightening composition having carboxylmethyl cysteamine, preferably N, N, S (tris) carboxylmethyl cysteamine, and an additional lightening agent and a cosmetically acceptable vehicle. The compositions and methods of the invention are effective to lighten skin, hair, lips, and/or nails.

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Melasma (CHLOASMA); Jun. 1999, Redding Dermatology Medical Group, Inc. pp. 1-2; URL: <http://www.reddingdermatology.com/melasma.htm>.
Chakraborty et al. “Effect of Arbutin melanogenic proteins in human melanocytes.” Pigment Cell Res. 1998; 11: 206-212.
Chakroborty et al. “Melanogenic regulatory factors in coated vesicles from melanoma cells.” J. Investigative Dermatology. vol. 93, No. 5, 616-620(1989).
Chakraborty et al. “Polymerization of 5,6-dihydroxyindole-2-carboxylic acid to melanin by the pmel 17/silver locus Protein.” Eur. J. Biochem. 236, 180-188 (1996).
Orlow et al. “Synthesis and characterization of malanins from Dihydroxyindole-2-carboxylic acid and Dihydrozyindole.” Pigment Cell Research. 5: 113-121 (1992).

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