Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Diagnostic or test agent produces in vivo fluorescence
Reexamination Certificate
2007-02-13
2007-02-13
Jones, Dameron L. (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Diagnostic or test agent produces in vivo fluorescence
C424S001110, C424S001650, C424S009100, C514S373000
Reexamination Certificate
active
10751232
ABSTRACT:
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.
REFERENCES:
patent: 4574124 (1986-03-01), Kabbe et al.
patent: 5106990 (1992-04-01), Ohno et al.
patent: 5346801 (1994-09-01), Watanabe et al.
patent: 5395619 (1995-03-01), Zalipsky
patent: 5492814 (1996-02-01), Weissleder
patent: 5496689 (1996-03-01), Ogawa
patent: 5631018 (1997-05-01), Zalipsky et al.
patent: 5840023 (1998-11-01), Oraevsky et al.
patent: 5968479 (1999-10-01), Ito et al.
patent: 5977538 (1999-11-01), Unger et al.
patent: 6083485 (2000-07-01), Licha et al.
patent: 6083486 (2000-07-01), Licha et al.
patent: 6150405 (2000-11-01), Proctor
patent: 6180085 (2001-01-01), Achilefu et al.
patent: 6180086 (2001-01-01), Achilefu et al.
patent: 6180087 (2001-01-01), Achilefu et al.
patent: 6183726 (2001-02-01), Achilefu et al.
patent: 6190641 (2001-02-01), Achilefu et al.
patent: 6217848 (2001-04-01), Achilefu et al.
patent: 6258340 (2001-07-01), Licha et al.
patent: 6258378 (2001-07-01), Schneider et al.
patent: 6264919 (2001-07-01), Achilefu et al.
patent: 6277403 (2001-08-01), Perez Mendez et al.
patent: 6329531 (2001-12-01), Turner et al.
patent: 6395257 (2002-05-01), Achilefu et al.
patent: 6406713 (2002-06-01), Janoff et al.
patent: 6534041 (2003-03-01), Licha et al.
patent: 6610322 (2003-08-01), Keller et al.
patent: 6673334 (2004-01-01), Achilefu et al.
patent: WO 96/00902 (1996-01-01), None
PCT,International Search Report, Date Mailed Feb. 13, 2002 (1 page).
Christopher C. Baker, M.D.,Epidemiology of Trauma Deaths, Amer. Jour. of Surg., vol. 150, 1980, pp. 144-150.
John Baldas et al,Preparation, HPLC Studies and Biological Behaviour of 99mTc- and 99mTcN-radiopharmaceuticals Based on Quinoline Type Ligands, Nucl. Med. Biol., vol. 19, No. 4, 1992, pp. 491-496.
Braun-Falco et al.,Liposome Dermatics, Greisbach Conference, Springer-Verlag, 1992, pp. 69-117.
Frank B. Cerra, M.D.,Multiple Organ Failure Syndrome, New Horizons: Multiple Organ Failure, Society of Critical Care Medicine, 1989, pp. 1-24.
Peter L. Choyke et al.,Hydrated clearance of gadolinium-DTPA as a measurement of glomerular filtration rate, Kidney International, vol. 41, 1992, pp. 1595-1598.
Cdr. P.D. Doolan, MC, USN, et al.,A Clinical Appraisal of the Plasma Concentration and Endogenous Clearance of Creatinine, Amer. Jour. of Med., vol. 32, 1962, pp. 65-79.
Richard B. Dorshow et al.,Monitoring physiological function by detection of exogenous flurosecent contrast agents, Optical Diagnostics of Biological Fludis IV, A. Priezzhev and T. Asakura, Eds., Procedings of SPIE, 1999, vol. 3599, pp. 2-8.
Dorshow et al.,Optical Detection of Hepatic and Renal Function, Bull. Am. Phys. Soc., vol. 42, No. 1, (1997) p. 681.
Richard B. Dorshow et al.,Noninvasive Fluorescence Detection of Hepatic and Renal Function, Journal of Biomedical Optics, vol. 3, No. 3, 1998, pp. 340-345.
James H. Flanagan, Jr., et al.,Near-Infrared Heavy-Atom-Modified Fluorescent Dyes for Base-Calling in DNA-Sequencing Applications Using Temporal Discrimination, Anal. Chem., vol. 70, No. 13, 1998, pp. 2676-2684.
P. Guesry et al.,Measurement of glomerular filtration rate by fluorescent excitation of non-radioactive meglumine iothalamate, Clincal Nephrology, vol. 3, No. 4, 1975, pp. 134-138.
L.Hansen et al.,Synthesis of the Sulphonate and Phosphonate Derivatives of Mercaptoacetyltriglycine, X-Ray Crystal Structure of Ha2[ReO(Mercaptoacetylglycylglycyl′Aminomethanesulphonate)]-3H2O, Metal-Based Drugs, vol. 1, No. 1, 1993, 31-39.
Lasic & Martin , Eds.,Stealth Liposomes, CRC Press, 1995, pp. 1-6, 13-62, 93-147, 197-209, 233-244.
Richard Lewis et al.,Comparative Evaluation of Urographic Contrast Media, Inulin, and 99mTc-DTPA Clearance Methods for Determination of Clomerular Filtration Rate in Clinical Transplantation, Transplantation, vol. 48, No. 5, 1989, pp. 790-796.
S. Lundqvist et al.,Iohexol Clearance for Renal Function Measurement in Gynaecologic Cancer Patients, Acta Radiologica, vol. 37, 1996, pp. 582-586.
Joanna Malicka, et al.,Metal-enhanced emission from indocyanine green: a new approach to in vivo imaging, Journal of Biomedical Optics, vol. 8, No. 3, Jul. 2003, pp. 472-478.
G. Muller et al. (ed.),Medical Optical Tomography, Functional Imaging and Monitoring, SPIE Optical Engineering Press, The International Society of Optical Engineering, Bellingham, WA 1993.
Roland Muller-Suur et al.,Glomerular Filtration and Tubular Secretion of MAG-3 in the Rat Kidney, The Journal of Nuclear Medicine, vol. 30, 1989, pp. 1986-1991.
Dennis L. Nosco et al.,Chemistry of technetium radiopharmaceuticals 1: Chemistry behind the development of technetium-99m compounds to determine kidney function, Coordination Chemistry Reviews, vol. 184, 1999, pp. 91-123.
Carlos A. Rabito et al.,Renal Function in Patients at Risk of Contrast Material-induced Acute Renal Failure: Noninvasive, Real-Time Monitoring, Radiology, vol. 186, No. 3, 1993, pp. 851-854.
G. Regel, M.D., et al.,Treatment Results of Patients with Multiple Trauma: An Analysis of 3406 Cases Treated between 1972 and 1991 at a German Level 1 Trauma Center, The Journal of Trauma, vol. 38, No. 1, 1995, pp. 70-77.
G.A. Reynolds et al.,Stable Heptamethine Pyrylium Dyes That Absorb in the Infrared, J. Org. Chem., vol. 42, No. 5, 1977, pp. 885-888.
Francoise Roch-Ramel et al.,Renal excretion and tubular transport of organic anions and cations, Oxford University Press, N.Y., Handbook of Physiology, Sec. 8, Neurological Physiology, vol. II, E.E. Windhager, Ed., 1992, pp. 2189-2262.
Morgan Sohtell et al.,FITC-inulin as a kidney tubule marker in the rat, Acta Physiol. Scand., vol. 119, 1983, pp. 313-316.
P.L. Southwick et al.,“One Pot” Fischer Synthesis of(2, 3, 3-Trimethyl-3-H-Indol-5-yl)-Acetic Acid, Derivatives as Intermediates for Fluorescent Biolabels, Org. Prep. Proced. Int. Briefs, vol. 20, No. 3, 1988, 279-284.
W. Newlon Tauxe ,Tubular Function, Nuclear Medicine in Clinical Urology and Nephrology, Appleton-Century-Crofts, Prentice-Hall, Inc., 1985, pp. 77-105.
Nicholas L. Tilney, M.D.,Acute Renal Failure in Surgical Patients, Causes, Clinical Patterns, and Care, Surgical Clinics of North America, vol. 63, No. 2, 1983, pp. 357-377.
Michael F. Tweedle, Ph.D. et al.,A Noninvasive Method for Monitoring Renal Status at Bedside, Investigative Radiology, vol. 32, No. 12, 1997, pp. 802-805.
Bruce E. VanZee, M.D. et al.,Renal Injury Associated with Intravenous Pyelography in Nondiabetic and Diabetic Patients, Annals of Internal Medicine, vol. 89, 1978, pp. 51-54.
Achilefu Samuel
Bugaj Joseph E.
Dorshow Richard B.
Jimenez Hermo N.
Periasamy Muthunadar P.
Jones Dameron L.
Mallinckrodt Inc.
Wood Herron & Evans LLP
LandOfFree
Light sensitive compounds for instant determination of organ... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Light sensitive compounds for instant determination of organ..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Light sensitive compounds for instant determination of organ... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3863070