Light microscope having acousto-optic tunable filters

Optical: systems and elements – Compound lens system – Microscope

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359308, 359371, 359495, G02B 2106, G02F 133

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active

058415777

ABSTRACT:
A light microscope comprises a light source and a first acousto-optic tunable filter responsive to the light source for producing two light streams of different polarization. A control circuit is provided for tuning the first filter to a plurality of frequencies. A mechanism, such as steering optics, is provided for combining the two light streams into a combined light stream. Input optics focus the combined light stream. A condenser, such as a darkfield condenser, receives the focused, combined, light stream and projects it onto a sample. A second acousto-optic tunable filter is responsive to light from the sample. A second control circuit is provided for tuning the second acousto-optic filter to a plurality of frequencies. The light from the second acousto-optic tunable filter may be captured and stored for future processing.

REFERENCES:
patent: 2674157 (1954-04-01), Heine
patent: 4560278 (1985-12-01), Schinozaki et al.
patent: 4806004 (1989-02-01), Wayland
patent: 4883963 (1989-11-01), Kemeny et al.
patent: 4896949 (1990-01-01), Melamed et al.
patent: 4940316 (1990-07-01), Brandt
patent: 5120961 (1992-06-01), Levin et al.
patent: 5131742 (1992-07-01), Schaff
patent: 5251057 (1993-10-01), Guerin
patent: 5377003 (1994-12-01), Lewis et al.
patent: 5497295 (1996-03-01), Gehly
patent: 5556790 (1996-09-01), Pettit
R. Nitschke, et al., Applicants of Electro-Optic and Laser Technology to Fluorescnece Microscopy, Quels '95/Summaries of papers presented at the Quantum Electronics and Laser Science Conference, vol. 16, 1995.
Elliot S. Wachman, et al., Imaging Acousto-Optic Tunable Filter with 0.35-Micrometer Spatial Resolution, Applied Optics, vol. 35, No. 25, 1 Sep. 1996.
Article Entitled "Technical Support Package, Compact, Automated, Frequency-Agile Microspectrofluorimeter," National Aeronautics and Space Administration, NASA Tech Briefs KSC-11611, Aug., 1995.
G. Gao and Z. Lin, "Acouto-optic Supermultispectral Imaging," Appl. Opt. 32, 3081-3086 (1993).
L. Cheng, T. Chao, M. Dowdy, C. LaBaw, C. Mahoney, and G. Reyes, "Multispectral Imaging Systems Using Acousto-optic Tunable Filter," Proc. Soc. Photo-Opt Instrum. Eng. 1874, 224-231 (1993).
T. Chao, G. Reyes, E. Hegbloom and L. Cheng, "Spatial-spectral Optical Pattern Recognition Using an Acousto-optic Tunable Filter Preprocessor," Proc. Soc. Photo-Opt. Instrum. Eng. 1959, 410-415 (1993).
R.B. Wattson, S.A. Rappaport, and E.E. Frederick, "Imaging Spectrometer Study of Jupiter and Saturn," Icarus 27, 417-422 (1976).
W.H. Smith, "Spectral Differential Imaging Detection of Planets About Nearby Stars," Publ. Astron. Soc. Pacif. 99, 1344-1353 (1987).
W.H. Smith and K.M. Smith, "A Polarimetric Spectral Imager Using Acousto-optic Tunable Filters," Exp. Astr. 1, 329-343 (1991).
D.A. Glenar, J.J. Hillman, B. Seif, and J. Bergstralh, "Acoustic-optic Imaging Spectropolarimetry for Remote Sensing," Appl. Opt. 33, 7412-7424 (1994).
H.R. Morris, C.C. Hoyt and P.J. Treado, "Imaging Spectrometers for Fluorescence and Raman Microscopy: Acousto-optic and Liquid Crystal Tunable Filters," Appl. Spectr. 48, 857-866 (1994).
P.J. Treado, I.W. Levin and E.N. Lewis, "High-Fidelity Raman Imaging Spectrometry: A Rapid Method Using an Acousto-optic Tunable Filter," Appl. Spectr. 46, 1211-1216 (1992).
M.D. Schaeberele, J.F. Turner II, and P.J. Treado, "Multiplexed Acousto-optic Tunable Filter Spectral Imaging Microscopy," Proc. Soc. Photo-Opt. Instrum. Eng. 2173, 11-20 (1994).
I. Kurtz, R. Dwelle and P. Katzka, "Rapid Scanning Fluorescence Spectroscopy Using an Acousto-optic Tunable Filter," Rev. Sci. Instrum. 58, 1996-2003 (1987).
P. Treado, I. Levin, E. Lewis, "Near-Infrared Acousto-optic Filtered Spectroscopic Microscopy: A Solid-State Approach to Chemical Imaging," Appl. Spectr. 46, 553-559 (1992).
K. Spring, P. Smith, "Illumination and Detection Systems for Quantitative Fluorescence Microscopy," Royal Microscopical Society, 265-278 (1987).
J. Hallikainen, J.P.S. Parkkinen, and T. Jaaskelainen, "Color Image Processing With AOTF," Proceeding of 6th Scandinavian Conference on Image Analysis; Oulu, Finland; Jun. 19-22, 1989, vol. 1, M. Pietikainen and J. Roning, eds., 294-300 (1989).
T. Chao, J. Yu, L. Cheng, and J. Lambert, "AOTF Imaging Spectrometer for NASA Applications: Breadboard Demonstration," Proc. Soc. Photo-Opt. Instrum. Eng. 1347, 655-663 (1990).
D.A. Glenar, J.J. Hillman, B. Seif, and J. Bergstrahl, "Polaris II: An Acousto-optic Imaging Spectropolarimeter For Ground Based Astronomy," Polarization and Remote Sensing, W.G. Egan, ed., Proc. Soc. Photo-Opt. Instrum. Eng. 1747, 92-101 (1992).
I.C. Chang, "Electronically Tuned Imaging Spectrometer Using Acousto-optic Tunable Filter," Proc. Soc. Photo-opt. Instrum. Eng. 1703, 24-29 (1992).
D.R. Suhre, M. Gottlieb, L.H. Taylor, and N.T. Melamed,"Spatial Resolution of Imaging Noncollinear Acousto-optic Tunable Filters," Opt. Eng. 31, 2118-2121 (1992).
Y. Chi, D.Cui, and J. Tang, "Study on the Characteristics of an Imaging Spectrum System by Means of an Acouto-optic Tunable Filter," Opt. Eng. 32, 2899-2902 (1993).

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