Light-mediated method and apparatus for the regional analysis of

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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435 5, 435 6, 435 71, 435 72, 435 721, 435 771, 435 405, 435 4051, 435176, 430 56, 430 60, 436518, C12Q 100, C12Q 168, G01N 3353

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061596817

ABSTRACT:
Compositions and methods are provided for performing regional analysis of biologic materials. The methods provided herein employ a photoresist layer that is established over a biologic material (which may be immobilized on a substrate). Regions of interest are selected and irradiated to expose specific regions of biologic material. Exposed biologic material may then be selectively analyzed using any of a variety of analytic methods.

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Flounders et al. (1997). Patterning of immobilized antibody layers via photolithography and oxygen plasma exposure. Biosensors and Bioelectronics. 12(6):447-456.

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