Ligands used for detecting prions

Details Ligands used for detecting prions Ligands used for detecting prions

2007-04-24

2007-04-24

Le, Long V. (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007500, C435S023000, C436S527000, C436S533000, C436S546000, C530S387100, C530S391100

Reexamination Certificate

active

10467612

ABSTRACT:
The invention relates to the use of specific ligand carriers for detecting prions, and to substances that are capable of binding to prions and that are subsequently used to detect prions.

REFERENCES:
patent: 2001/0005578 (2001-06-01), Prusiner et al.
patent: 2001/0010918 (2001-08-01), O'Connor
patent: 2005/0208608 (2005-09-01), Raven et al.
patent: 197 30 132 (1999-02-01), None
patent: WO 00/29850 (2000-05-01), None
“Binding of the Protease-Sensitive Form of Prion Protein PrP to Sulfated Glycosaminoglycan and Congo Red”, Caughey et al., Journal of Virology, vol. 68, No. 4, Apr. 1994, pp. 2135-2141.
“Characterization and Polyanion-binding Properties of Purified Recombinant Prior Protein”, Brimacombe et al., Biochem. J., 1999, pp. 605-613.
International Search Report in PCT/EP02/01451 dated Oct. 11, 2002.
International Preliminary Examination Report in PCT/EP02/01451 dated Jan. 9, 2003.

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