Ligands to enhance cellular uptake of biomolecules

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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5303917, 530395, 536 231, C07K 1600

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059945176

ABSTRACT:
Oligodeoxynucleoside methylphosphonate neoglycopeptide conjugates and related compounds for tissue specific delivery of biologically stable, nonionic oligodeoxynucleoside analogs into cells.

REFERENCES:
Bonfils, et al, 1994, "Drug targeting: Synthesis and endocytosis of . . . " Nucleic Acids Res. 20(17): 4621-29.
Zaia, et al, 1988, "Inhibition of human immunodeficiency virus by . . . " J. Virol. 62(10): 3914-3917.
Merwin, et al, 1994, "Targeted Delivery of DNA Using . . . " Bioconjugate Chem. 5: 612-620.
Agris, et al, 1986, "Inhibition of vesicular Stomatitis Virus . . . " Biochemistry 25: 6268-6275.

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