Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-04-26
2010-11-16
Allen, Marianne P (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200
Reexamination Certificate
active
07833722
ABSTRACT:
The present invention provides a method of screening an agonist/antagonist of a G protein-coupled receptor protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, or a salt thereof, which comprises using the receptor protein or its salt and a ligand or its salt; and so on. The screening method of the present invention is useful for screening an agent for the prevention/treatment of nervous system diseases or neuropathic pains.
REFERENCES:
patent: 6555339 (2003-04-01), Liaw et al.
patent: 2004/0176344 (2004-09-01), Rooney
patent: 2 360 586 (2001-09-01), None
patent: WO-94/12635 (1994-06-01), None
patent: WO-01/68842 (2001-09-01), None
patent: WO-03/025138 (2003-03-01), None
patent: WO-03/071272 (2003-08-01), None
Carol J. Raport et al.; “New Members of the Chemokine Receptor Gene Family”, Journal of Leukocyte Biology, vol. 59, pp. 18-28, Jan. 1996.
Rainer Blasius et al., “A Novel Orphan G Protein-Coupled Receptor Primarily Expressed in the Brain is Localized on Human Chromosonal Band 2q21”; Journal of Neurochemistry, vol. 70, No. 4, pp. 1357-1365 (1998).
Charles De Smet et al.; “A Novel Seven Transmembrane Receptor Induced During the Early Steps of Astrocyte Differentiation Identified by Differential Expression;” Journal of Neurochemistry, 81, pp. 575-588 (2002).
Walter E. Muller; δ-Aminolevulinic Acid: Influences of Synaptic GABA Receptor Binding May Explain CNS Symptoms of Porphyria; Ann Neurol. 2: pp. 340-342 (1977).
Martin J. Warren et al.; “Lead Poisoning, Haem Synthesis and 5-aminolaevulinic Acid Dehydratase”; TIBS 23, pp. 217-221 (Jun. 1998).
Steen J. Madsen, et al.: “Repetitive 5-aminolevulinic acid-mediated photodynamic therapy on human glioma spheroids,” Journal of Neuro-Oncology 62: 243-250, 2003.
Fujii Ryo
Harada Masataka
Hinuma Shuji
Allen Marianne P
Takeda Pharmaceutical Company Limited
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